"Bittersweet is a poisonous plant that has a long history of use in the treatment of skin diseases, warts, tumours, felons etc. It should be used with caution and only under the supervision of a qualified practitioner, this is a poisonous plant that, in excess, paralyzes the central nervous system, slows the heart and respiration, and lowers temperature, causing vertigo, delirium, convulsions and death[21, 238]. See also the notes above on toxicity. All parts of the plant are alterative, anodyne, depurative, mildly diuretic, emetic, expectorant, hepatic, mildly narcotic and purgative[4, 7, 9, 13, 21, 165]. The plant is chiefly used as an alterative when taken internally in the treatment of a range of skin diseases, it is also used in the treatment of arthritis, rheumatism, bronchial congestion, heart ailments, ulcerative colitis and jaundice[4, 218, 238]. Externally, the plant is used to treat skin eruptions, ulcers, rheumatism and cellulite"
- PFAF References